VERMODJE – Testover C

Description

A synthetic Testosterone derivative known as Testosterone Cypionate is a 17 (beta)-cyclopentylpropionate ester that is oil-soluble. Its advantage over other testosterone derivatives is that it releases hormones slowly after injection and has a longer half-life. It was made by the business Pharmacia.

Therapeutic indication

Testosterone Cypionate is an androgen used to treat low or absent testosterone. In guys who exhibit symptoms brought on by a lack or absence of endogenous testosterone, testosterone cypionate is utilised. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterised by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumours, trauma or radiation.

Why choose Testosterone Cypionate over conventional medicine?

Within 24 hours of treatment, blood testosterone levels rise to 400% over baseline after the administration of ester derivatives of testosterone like testosterone cypionate. After the initial injection, these androgen levels are high for 3 to 5 days. 3 After testosterone cypionate is administered intramuscularly, the level of plasma testosterone continuously fluctuates, causing changes in libido and mood as well as some local inflammation.

Pharmacological actions

Activation of the androgen receptor (directly or through DHT) and conversion to estradiol and activation of specific oestrogen receptors are the two major ways that testosterone affects humans and other animals. The cytoplasmic enzyme 5-alpha-reductase transports free testosterone (T) into the target tissue cells, where it can attach to the androgen receptor or be converted to 5-alpha-dihydrotestosterone (DHT). DHT has around 2.5 times the androgenic potency of T because it attaches to the same androgen receptor much more firmly than T does. The structural transformation of the T-receptor or DHT-receptor complex enables it to go into the cell nucleus and attach specifically to certain nucleotide sequences of the chromosomal DNA. Hormone response elements (HREs), which control the transcriptional activity of certain genes and result in the androgen effects, are the sites of binding.

Usage Directions

It is given by injection into muscle or subcutaneously, once every one to four weeks, depending on clinical indication.

Side effects

• chest pain
• stroke
• weakness in one side of your body
• slurred speech