VERMODJE – Testover U

Description

The ester prodrug of Testosterone, Testosterone Undecanoate, has a mid-chain fatty acid at the carbon 17 position.  To create testosterone that could be taken orally, fatty acid esterification of testosterone was created.  For testosterone replacement therapy in adult males with hypogonadism, testosterone undecanoate is available in both oral and intramuscular forms.

Therapeutic indication

An androgen called testosterone undecanoate is prescribed to adult men with primary hypogonadism and hypogonadotropic hypogonadism as part of testosterone replacement treatment. For diseases linked to a lack or absence of endogenous testosterone in adult males, testosterone undecanoate is advised as a kind of testosterone replacement treatment. These circumstances include: primary hypogonadism, either congenital or acquired.

Why choose Testosterone Undecanoate over conventional medicine?

An essential component of male sexual development, testosterone is an endogenous male hormone that controls hematopoiesis, body composition, and bone metabolism.

Pharmacological actions

Endogenous non-specific esterases break down testosterone undecanoate in the bloodstream to produce the compound’s active ingredient, testosterone. Pharmacologically speaking, the undecanoate side chain is inactive. 5 reductase can further transform testosterone into its more physiologically active form, dihydrotestosterone (DHT). The androgen receptor, which is extensively expressed in many tissues, including the bone, muscle, prostate, and adipose tissue, is the mechanism through which testosterone and DHT exert their effects.

Usage Directions

It is taken by mouth or given by injection into muscle.

Side effects

• virilization
• hirsutism
• clitoral enlargement
• breast atrophy
• menstrual irregularities